V Tight Gel Apply topical over-the-counter anti-fungal or drying grain, such as those that contain need a shorter treatment time, while azoles are more affordable but need a longer period treatment time. Home solutions for Jock Itch is also useful. Tea tree oil can also be used since it is a organic anti-fungal. Garlic is also known to have anti-fungal functions because it contains allicin. Oral medications for sickness may alter the effectiveness of warfarin, an anticoagulant drug that cuts down on clots ability of your blood vessels.